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A world without rebates? How will the Part D market react to the new proposed safe harbor for rebates?27 March 2019 - By Bruce S. Pyenson and Amy Kwong - Article

This paper describes how the proposed rule to eliminate the long-standing safe harbor protection for prescription drug rebates paid to Medicare Part D sponsors and pharmacy benefit managers may affect the Medicare Part D market.

Multiple sclerosis: New perspectives on the patient journey: 2019 update20 March 2019 - By Bruce S. Pyenson and Samantha Tomicki - Article

Claims-based predictive modeling may help identify patients at risk for multiple sclerosis and assess disease burden.

Applying machine learning techniques to identify undiagnosed patients with exocrine pancreatic insufficiency14 February 2019 - By Feng Han and Jaime Vora and Jeffrey Gomberg and Monica Son and Motoharu Dei and Nikhil Khandelwal and Bruce S. Pyenson and Maggie Alston - Article

This study develops a machine learning model that identifies patients in a commercial medical claims database who likely have exocrine pancreatic insufficiency but are underdiagnosed.

Can voluntary POS rebates work for Medicare Part D?12 February 2019 - By Jennifer Carioto and Gabriela Dieguez and Bruce S. Pyenson - Article

This report examines why Medicare Part D plans that share manufacturer rebates at the point of sale under a voluntary system will likely have a rather high premium relative to market averages.

Including dementia in the Part C Medicare risk adjuster: Health services issues11 February 2019 - By Bruce S. Pyenson and Charles Steffens - Article

The Centers for Medicare and Medicaid Services released its proposed 2020 risk score methodology for Medicare Advantage plans in December, and it describes proposed updates to the existing Hierarchical Condition Category (HCC) risk adjustment model and suggests an alternative model, which includes two HCCs for dementia.

The utility of ICER reports for private payer budgeting: Budget impact analyses17 January 2019 - By Tia Goss Sawhney and Bruce S. Pyenson and Eric Buzby - Article

This report identifies several disconnects between the Institute for Clinical and Economic Review’s work and its potential use by private payers to analyze the impact of new drugs on their budgets.

Computed tomography colonography less costly than colonoscopy for colorectal cancer screening of commercially insured patients21 December 2018 - By Judy Yee and Tia Goss Sawhney and Bruce S. Pyenson and Michele M. Berrios - Article

For colorectal cancer screening, does computed tomography have a cost advantage relative to optical colonoscopy for the commercially insured U.S. population?

Pharma APMs: A learning curve awaits you, pharma02 October 2018 - By Maggie Alston and Bruce S. Pyenson - Article

There are some valuable lessons for pharmaceutical manufacturers in provider alternative payment models (APMs), but whether pharmaceutical APMs succeed or fail will depend on finding solutions to operational and logistical challenges—some of which are unique to the pharmaceutical industry.

The utility of ICER reports for private payer drug coverage decision-making: Cost-effectiveness assessments19 September 2018 - By Tia Goss Sawhney and Bruce S. Pyenson and Eric Buzby - Article

This report identifies several disconnects between the Institute for Clinical and Economic Review’s (ICER) work and its potential use by private payers, which could help explain why private payers make little use of ICER assessments when making coverage decisions.

Pharma APMs: Can the industry learn to play well with others?05 September 2018 - By Maggie Alston and Bruce S. Pyenson - Article

The dynamics of alternative payment models suggest a potential win for insurers, pharmaceutical manufacturers, and patients through an emphasis on reducing cost and improving outcomes.


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